Studied at the Bristol Medical School in 1884 and at the Royal Infirmary, where he won the Tibbits Memorial Prize for Practical Surgery, then at St Bartholomew's Hospital. After acting as House Surgeon, House Physician, and Anaesthetist at the Bristol Royal Infirmary, also as Curator of the Museum, he was subsequently Resident Medical Officer from 1895-1902. From 1879 there was an informal clinic for treatment of diseases of the ear; Mole was elected Assistant Surgeon in charge of the Aural Department in 1902, in connection with which he made some models of the labyrinth in fusible metal, and was an active member of the Otological Society, which became later a Section of the Royal Society of Medicine, on which he served as a Member of Council. He became Surgeon to the Infirmary in 1909, relinquishing his charge of the Ear Department, and was Teacher of Clinical Surgery in the University of Bristol until 1916. Asthma had afflicted him from childhood and had seriously handicapped his professional career, yet he was able, in addition to other work, to act as Secretary to the Bristol Medico-Chirurgical Society from 1903-1907. He had held for two months in 1914 a commission in the RAMC (T), but was obliged to resign on account of ill health. He also resigned in 1916 his post of Surgeon to the Infirmary. He died at 24 College Road, Clifton, Bristol, on December 21st, 1917. He had married in 1913 and was survived by his widow and two sons; a daughter was born posthumously.