Born 20 June 1880 at 11 Eldon Square, Newcastle-on-Tyne, the youngest child, with a brother and a sister, of John Hope, MRCS 1865, and Jessie Anne Martin, his wife. John Hope died in February 1883, and the children were brought up by their grandfather. Charles Hope was educated at Clifton College and the Newcastle Medical School, graduating in the University of Durham in 1903. After holding resident posts at the Royal Victoria Infirmary, Newcastle, he came to London in 1908 as resident anaesthetist at St Mary's Hospital, and later became clinical assistant to G William Hill, MD, in the throat department. He was also registrar and assistant surgeon to the Throat Hospital, Golden Square. He transferred to King's College Hospital on appointment as assistant surgeon for diseases of the throat under Sir St Clair Thomson in 1914, and became surgeon for the throat and nose in 1922, and senior surgeon to the ear, nose, and throat departments on their amalgamation in 1932; he retired in 1941 as consulting surgeon. He was also consulting surgeon to the ear, nose, and throat departments of Finchley Memorial Hospital, and to the nose and throat department of the Royal Eye Hospital, Southwark. He served at the St John's Ambulance Brigade Hospital in France with the British Expeditionary Force during the first world war 1914-18, with the honorary rank of major, RAMC. He was created OBE and Officer of the Order of St John of Jerusalem. In the second world war he served as full-time surgeon, 1939-41, at Horton Hospital, Epsom, under the Ministry of Health's emergency medical service. Hope practised at 13 Queen Anne Street, W; he retired, owing to ill-health, in 1941 to 5 The Avenue, Knaresborough, Yorkshire, where he died, aged 68, on 21 April 1949. A memorial service was held in King's College Hospital chapel. Hope never married. His recreations were gardening and carpentry, and he took a yearly holiday salmon-fishing in Scotland. "Charlie" Hope was a man of generous and kindly nature; as a surgeon, he was thorough, patient, and gentle. He was honorary secretary 1923-26, and president, from 1926 for many years, of the Students Club and Societies' Union at King's College Hospital. He left a third of the residue of his fortune to King's College Hospital, and two-thirds to its Medical School.