Born 22 February 1873, the fifth child and third son of the Rev Robert Vaughan Pryce, DD, and Elizabeth Tippetts his wife. His father was principal of New College, London University, the Congregational theological college, from 1889 to 1907, and died in 1917; his grandfather George Pryce, FSA, had been City Librarian of Bristol. Pryce was educated at University College, London, St John's College, Cambridge, and St Bartholomew's Hospital. He took second-class honours in the Natural Sciences Tripos, 1895, and first-class honours in surgery and midwifery at the MB, BCh examination in 1902. After serving as a dresser to Sir Henry Butlin, he went as house surgeon to the Portsmouth Hospital in 1899, contracted typhoid, and then took a sea-voyage to New Zealand to recoup his health. In 1900 he was house surgeon to Butlin at St Bartholomew's and also filled the post of extern midwifery assistant and clinical assistant in the throat department, Vaughan Pryce practised at Brighton from 1901 to 1905, and from 1905 till the end of 1930, when he retired, at Stamford Hill, London, N. He was anaesthetist to the Tottenham Hospital and the German Hospital. During the war of 1914-18 he was civil surgeon to the Mile End and the City of London military hospitals. In 1905 Pryce married Marian Frances Violet Clarke, who survived him but without children. Mrs Vaughan Pryce's sister married H G Pinker, FRCS, who had been a fellow-student with Pryce at St Bartholomew's. He died suddenly on 6 December 1946 at 40a High Street, Welshpool, Montgomery, aged 73.