Born at Hollingworth, Cheshire, in the Longdendale Valley, where his father had settled in medical practice whilst the railway, which became the Great Central Railway, was being made, and had gathered a large and wide country practice. Pomfret went to Marlborough School, and then to Owens College Medical School, and, having qualified, was appointed House Surgeon at the Royal Infirmary, Manchester. Next he worked for and passed the FRCS, and then returned to Owens College for the degree of the Victoria University, was elected to a Berkeley Fellowship, and carried out in the Pharmacological Laboratory a research on nitrous and nitroso groups of organic compounds, their physiological actions and therapeutic uses, which formed a thesis for the MD, under the title *Nitrosophenol or Quinonoxine* (Manchester, 1889), awarded a Gold Medal, and "Organic Oximides: a Research on their Pharmacology" (*Phil Trans*, 1896, clxxxvi, 223). Reverting to surgery, he became Surgical Registrar at the Royal Infirmary, and practised in Moseley Street. On the death of his brother-in-law, Dr Harold Wylde, who had succeeded to the elder Pomfret's practice, he returned to Hollingworth in 1900, carried on the family medical practice, was Medical Officer of Health and Public Vaccinator for the District, and Referee under the Workmen's Compensation Act. He likewise kept up his Manchester connection, and acted as Assistant Surgeon and Pathologist to the Ancoats Hospital. Pomfret was an alert and genial personality, a warm friend, and an able surgeon. He travelled, and devoted his leisure to music. He died at Hollingworth on November 18th, 1912.