Born at Lincoln on 3 February 1880, the fifth child and third son of Henry Clarke, master dyer and cleaner, and Sally Shooter Jackson, his wife. He was educated at Lincoln Grammar School and at St Mary's Hospital, where he won the senior scholarship in natural science, a scholarship in pathology, and a prize in practical surgery. He took first-class honours in anatomy at the London MB examination in 1888. At St Mary's he was successively house surgeon, house physician, ophthalmic assistant, pathologist, curator of the museum, and senior demonstrator of anatomy. After serving. as. clinical assistant at the Royal London Ophthalmic Hospital (Moorfields), he eventually became consuiting surgeon to the Hampstead and North-West London Hospital and to the Royal National Orthopaedic Hospital. He was a frequenter of professional societies and was at one time honorary secretary of the Harveian society. He practised at 18 Portland Place, and later at 1 Park Crescent, W1. Clarke married Miss Riley, who died before him; they had no children. He died on 4 December 1940. Publications:- *Post-mortem examinations in medico-legal and ordinary cases*. London, 1896. *Surgical pathology and principles*. London, 1897. *Orthopaedic surgery*. London, 1899. *Congenital dislocation of the hip*. London, 1910. *Protozoa and disease*, vols. 1-4. London, 1903, 1908, 1912, 1915. *Protista and disease*, 1 vol. London, 1922.