The son of Judge Griffith of the County Court, Wolverhampton Circuit, previously Attorney-General, Cape Colony. He entered Trinity Hall, Cambridge, in 1882, and, after gaining a scholarship, graduated with a first class in the Classical Tripos in 1885. He then studied at St Thomas's Hospital, where he was House Surgeon. In 1893 he was appointed Resident Medical Officer at the Royal Free Hospital, but exhibiting signs of pulmonary tuberculosis was obliged to go on a voyage to the West Indies and then to Cape Colony. He spent a year at Aliwal, and he acted as Medical Officer at Quiting in Basutoland. In 1896 he was appointed House Surgeon to the Kimberley Hospital, and was afterwards President of the Griqualand West Branch of the British Medical Association and was a member of the Pathological Society. He died of phthisis on November 17th, 1898, at Kimberley. Whilst there he exhibited an original and inquiring mind and a rich Irish humour which coloured his descriptions of diseases he had observed among the natives.