Born at Liverpool on 5 June 1859, the second son and youngest child of Frederick Worthington, MRCS, LSA, of Abercrombie Street, Liverpool, surgeon to the Liverpool Lock Hospital, and Sophia de la Serre his wife. He was educated at Clifton College and at Guy's Hospital, where he served the office of house surgeon. He afterwards acted as house surgeon at the Female Lock Hospital, Paddington, and was for a time physician to the Chesterfield and North Derbyshire Hospital. The greater part of his life was spent in general practice at Warwick. He died at 23 Jury Street, Warwick, on 14 September 1935, survived by his wife and four children, two sons and two daughters, and was buried in Warwick. He married Alice Livingstone Lowndes on 20 April 1899. He left £100 to the Warneford, Leamington, and South Warwickshire General Hospital.