Practised at Abbey Square, Chester, where he was Surgeon to the General Infirmary and to the Lying-in Institution. He died in 1863 or 1864, long surviving George Harrison, junr (? his son) (qv), and his successor as Surgeon to the General Infirmary.

Practised at St John Street, Great Broughton, Chester, and was Surgeon to the General Infirmary in succession to George Harrison, senr (? His father) (qv), whom he predeceased on or before October 26th, 1849.