Third son of the Rev Samuel Alford, of Queen's College, Oxford, who graduated BA in 1797 and MA in 1800. He was born at Curry Rivel, near Taunton. The Alford family had held property in West Somerset from the middle of the sixteenth century, and son had succeeded father in the church for several generations. Henry Alford (1810-1871), Dean of Canterbury, and Bishop Alford were cousins of Henry Alford, FRCS. Alford became a house pupil at the Bristol Infirmary in 1822, and five years later came to London to complete his medical education at St Bartholomew's Hospital. After qualifying, he practised at Ilminster until he was appointed Surgeon to the Somerset and Taunton Hospital in 1830, when he settled in Taunton. He resigned his office in 1859 and was appointed Consulting Surgeon. He was Bailiff of Taunton, a churchwarden of St Mary's Church, a keen politician, and a hearty supporter of Sir Robert Peel in his policy of repealing the Corn Laws. He died at South Road, Taunton, in his 92nd year on June 29th, 1898. He married twice, and by his first wife left four children. His son, Henry J Alford, MD MRCS, was also educated at St Bartholomew's Hospital, and was Medical Officer of Health for Taunton.