Born at East Rudham, Norfolk, where his father was in practice; educated at Lynn Grammar School and Epsom College. His younger brother was Sir Alan Reeve Manby (qv). He studied at Guy's Hospital and then settled in practice at Wolverhampton, where he was Surgeon to the Wolverhampton and Staffordshire General Hospital, a member of the Town Council and in 1888 Mayor. He interested himself in sanitary improvements, the Artisans' Dwellings Scheme, the Infectious Diseases Hospital, and was Medical Officer of Health of the Cannock Rural District during a severe epidemic of small-pox. He was devoted to the interests of the Free Library. He also became Brigade Surgeon of the Staffordshire Infantry Volunteer Brigade, and later Surgeon Major of the South Staffordshire Regiment and Army Medical Reserve. For his activity in the St John Ambulance Association he was made Hon Associate of the Grand Priory. He founded the Wolverhampton Branch of the Society for the Prevention of Cruelty to Children, and assisted in the formation of the Wolverhampton Nursing Institution as a Jubilee Memorial. He discussed in the *Lancet* (1890, ii, 640) the subject of Liquor Trade Licensing. At the British Medical Association he represented the Birmingham and Midland Counties Branch from 1874-1883. He practised at 11 King Street, Wolverhampton, and after suffering from influenza went to Guernsey in search of health, and died there on July 1st, 1891. Some four hundred Volunteers followed the military wagon bearing the coffin, and the municipal officials attended his funeral.