Arthur Joseph Wrigley (Joe) was born at Clitheroe, Lancashire, on 5 May 1902, the son of Canon Joseph Wrigley and after attending the Royal Grammar School, Clitheroe, and later Rossall School, he entered St Thomas's Hospital Medical School, qualifying in 1924. He gained a distinction in pathology in

Brews was the son of a general practitioner, Richard Vincent Brews, LRCSI, and his wife Edith Manifold; he was born in North Woolwich in 1902. He was educated at the Merchant Taylors' School and became a medical student at the London Hospital in 1920. After gaining many prizes he qualified in 1924,